In October 2017, through the collaboration of the American Institute of Biological Sciences and the American Society for Gravitational and Space Research (ASGSR), BioScience Talks hit the road. We attended ASGSR's annual meeting in Seattle, Washington, where we had the chance to speak with numerous presenters and participants about a diversity of space-related topics, ranging from the International Space Station (ISS) and zero-gravity plant growth to human health at high altitudes and space-based pharmaceutical development. This special episode brings together the foremost thought leaders in space-related biology and physical science, highlighting the broad spectrum of research being conducted at unique venues such as and the ISS. Interviewees included: Cindy Martin-Brennan, Executive Director of ASGSR Anna-Lisa Paul and Robert Ferl, University of Florida Michael Roberts, Center for the Advancement of Science in Space Ken Savin, Center for the Advancement of Science in Space Jonathan Clark, Baylor College of Medicine and the Florida Institute for Human and Machine Cognition Learn more: Join ASGSR! Attend the 2018 Annual Meeting in Washington, DC. Listen to archived webcasts of the 2017 meeting. Subscribe on iTunes. Subscribe on Stitcher. Catch up with us on Twitter. Closing music courtesy of Lakey Inspired.